Which criterion for Substance Use Disorder involves continuing use despite knowledge of persistent physical or psychological problems likely caused or worsened by the substance?

• A. Craving
• B. Continued use despite knowledge of problems
• C. Withdrawal
• D. Tolerance

Answer: (B)

This criterion captures continuing to use in the face of harm. It shows a person keeps using the substance even after recognizing that it is causing or worsening physical or psychological problems, which is a hallmark of impaired control and persistent use.

This is distinct from craving (the urge to use), withdrawal (physical or psychological symptoms when not using), and tolerance (needing more of the substance to achieve the same effect). For example, someone might keep drinking despite developing liver problems or worsening anxiety, demonstrating this pattern of use despite known adverse effects.